Since 2015, Riley has received both cognitive behavioral therapy and antidepressants for his own depression. Throughout his treatment, he wondered—are antidepressants effective? Do short-term talking therapies actually work? And what treatments are on the horizon for those who don’t respond to these first-line treatments? Expanding from his own experience, he tracks treatments through history, from the “talking cure” to electroconvulsive therapy to magic mushrooms.
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