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Bottle of lies : the inside story of the generic drug boom
2019
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Summary

A NEW YORK TIMES BESTSELLER

From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale--The Jungle for pharmaceuticals

Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?

Katherine Eban's Bottle of Lies exposes the deceit behind generic-drug manufacturing--and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.

The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?

A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world's greatest public-health innovation has become one of its most astonishing swindles.

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Table of Contents
Author's Notep. xi
About the Reportingp. xvii
Important People and Placesp. xix
Prologuep. 1
Part IShifting Ground
Chapter 1The Man Who Saw Furtherp. 9
Chapter 2The Gold Rushp. 17
Chapter 3A Slum for the Richp. 31
Chapter 4The Language of Qualityp. 41
Chapter 5Red Flagsp. 57
Part IIIndia Rises
Chapter 6Freedom Fightersp. 69
Chapter 7One Dollar a Dayp. 81
Chapter 8A Clever Way of Doing Thingsp. 91
Chapter 9The Assignmentp. 101
Part IIIA Cat-And-Mouse Business
Chapter 10The Global Cover-Upp. 121
Chapter 11Map of the Worldp. 137
Chapter 12The Pharaoh of Pharmap. 149
Part IVMaking a Case
Chapter 13Out of the Shadowsp. 161
Chapter 14"Do Not Give to FDA"p. 169
Chapter 15"How Big Is the Problem?"p. 179
Chapter 16Diamond and Rubyp. 195
Chapter 17"You Just Don't Get It"p. 207
Part VDetectives in the Dark
Chapter 18Congress Wakes Upp. 221
Chapter 19Solving for Xp. 233
Chapter 20A Test of Endurancep. 245
Chapter 21A Deep, Dark Wellp. 259
Chapter 22The $600 Million Jacketp. 273
Part VIThe Watershed
Chapter 23The Light Switchp. 293
Chapter 24We Are the Championsp. 311
Chapter 25Crashing Filesp. 321
Chapter 26The Ultimate Testing Laboratoryp. 337
Part VIIReckonings
Chapter 27Flies Too Numerous to Countp. 357
Chapter 28Standingp. 377
Epiloguep. 395
Acknowledgmentsp. 411
Glossaryp. 415
Notesp. 421
Indexp. 463
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